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Beilstein J. Org. Chem. 2015, 11, 837–847, doi:10.3762/bjoc.11.93
Graphical Abstract
Figure 1: Comparing the entropy loss during ligand–receptor interactions in dependence of the rigidity of the...
Scheme 1: Selection of three polymer carriers differing with respect to backbone flexibility, and morphology ...
Figure 2: Representative ITC-measurements conducted at 8 °C with the peptide–polymer conjugates A) pHPMA-1 an...
Figure 3: Enthalpic and entropic contributions to the free energy of binding processes of multivalent peptide...
Figure 4: MD simulations over time (0–100 ns) yielding A) the mean sulfur distance between two peptides at th...
Figure 5: MD simulation image showing the interaction of two dextran–peptide conjugates with three tandem WW ...
Beilstein J. Org. Chem. 2015, 11, 701–706, doi:10.3762/bjoc.11.80
Figure 1: Phage display was used to find an optimized binding partner for FBP21-tWW. A) Schematic representat...
Scheme 1: Schematic representation of the synthesis of hPG-peptide conjugate 2.
Figure 2: A) ITC measurement with FBP21-tWW and hPG-peptide conjugate 2, the KD value is 17.6 ± 0.016 μM. B) ...